Processing pipeline for pediatric brain MRI

• Study Overview

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Neurological rare diseases are caused by pathological genes that affect the nervous system and cause clinical symptoms. To better understand and diagnose these diseases, researchers have studied neuroimaging endophenotypes, which are quantitative biological traits that reflect the function of a specific biological system and are heritable. In particular, studies have focused on using MRI to identify abnormal features that may be associated with these diseases. The researchers analyzed MRI data from 150 patients with neurological rare diseases, extracting quantitative features such as brain tissue volume, T2 hyperintensity, and myelination index, which can help diagnose and treat these diseases more accurately.

• Processing Pipeline For Pediatric MRI

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⁻  Pipeline Design

⁻  Prerequisite

⁻  Utils

⁻  Preprocessing (download)

⁻  Pipeline For the Volumetry (download)

⁻  Pipeline For the Extraction of the White Matter Hyperintensity (download)

⁻  Pipeline For the Extraction of T2 High Signal Lesion (download)

⁻  Pipeline For the Extraction of the Myelination Index (download)

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• MRI Features of the Neurologically Rare Disease From 110 T1, T2, FLAIR MRI Sets